Laboratory of Cell Differentiation

Research laboratory at the Department of Experimental Biology at Masaryk University

News

22 Feb

New paper in NEOPLASIA

New paper "c-Myb interferes with inflammatory IL1α-NF-κB pathway in breast cancer cells" by Monika Dúcka has been recently published in NEOPLASIA.

2 Feb

Barbora awarded with EMBO Short-Term Fellowship

Our PhD student Barbora Pavlatovska was awarded with EMBO Short-Term Fellowship to spent two months at the Institute of Cancer Research, Medical University of Vienna.

1 Feb

Jiri Kohoutek joined our team

Jiri Kohoutek joined our team as a new Assistant Professor. A warm welcome to our lab and good luck in your work!

25 Jan

3rd best poster in PragueONCO 2021

Poster by Kamila Říhová et al. was awarded as the 3rd best poster presentation in PragueONCO 2021. Congratulations!

5 Jan

2021 PhD position available

We are seeking a motivated PhD student for projects-funded position in our laboratory. The candidate is expected to work on the running projects of the lab dealing with Tumor-derived inflammatory factors and anti-tumor immunity in breast cancer metastasis. Please contact Petr Benes, PhD at pbenes@sci.muni.cz. Position is opened from September 2021.

22 Dec 2020

All the best in 2021

Merry Christmas and all the best for the coming year to all our colleagues and partners.

15 Dec 2020

New paper published in "Frontiers in Oncology"

New paper "Lactic Acidosis Interferes With Toxicity of Perifosine to Colorectal Cancer Spheroids: Multimodal Imaging Analysis" by Barbora Pavlatovská has been recently published in FRONTIERS IN ONCOLOGY.

11 Nov 2020

New review article published in "Cancers"

A review article "Trop2: Jack of All Trades, Master of None" by Sara Lenart et al. has been recently published in CANCERS.

15 Sep 2020

Petra and Martina defended their diploma theses

Petra Brisudová and Martina Kučeríková successfully defended their diploma theses. We wish them good luck in their future career.

18 Aug 2020

Best Software and Instrumentation Paper

Paper co-authored by Jarmila Navrátilová and Barbora Pavlatovská "Quantitative Assessment of Anti-Cancer Drug Efficacy From Coregistered Mass Spectrometry and Fluorescence Microscopy - Images of Multicellular Tumor Spheroids" published in Microscopy and Microanalysis was selected as the Best Software and Instrumentation Paper for 2019. Congratulations!

30 Apr 2020

New co-authored paper in "Analytical Chemistry"

New paper "Ozonization of Tissue Sections for MALDI MS Imaging of Carbon-Carbon Double Bond Positional Isomers of Phospholipids", co-authored by Lucka Knopfova and Jarmila Navratilova, was recently published in Analytical Chemistry.

20 Dec 2019

New papers in "Analytical Chemistry" and "Microscopy and Microanalysis"

Two new papers by team of Jarmila Navratilova describing new approach of MALDI-MSI and fluorescence microscopy data coregistration has been just published.

More news

We focus on cancer cells research using techniques of molecular and cellular biology

The laboratory was established in 1994 to investigate principles of cancer cell proliferation, differentiation, cell death and metastasis. As a model we use cancer cell lines of various origin, patient-derived organoids and in vivo mouse models. Using multiple techniques of molecular and cellular biology, we investigate function of specific genes and the role of tumor microenvironment in these processes. We are also interested in testing the tumor suppressing effects of various anti-cancer drugs.

The aim of our work is to perfom the basic experiments in tissue cultures, confirm their results in laboratory mice and to participate in clinical studies to provide benefits to cancer patients.

Research activities

Contact

prof. RNDr. Jan Šmarda, CSc.

Head of the laboratory

Phone:	+420 549 49 1416
E‑mail:

Organizational structure:
Masaryk University › Faculty of Science › Department of Experimental Biology › Section of Genetics and Molecular Biology › Laboratory of Cell Differentiation