News | Laboratory of Cell Differentiation

3 Jul

Anděla and Veronika defended their diploma theses

Anděla Žáčková and Veronika Mikolajková defended successfuly their diploma theses. Congratulations and thank your for your effort. It was great to have you in our team.

21 May

Veronika won the Best Poster Award at the 25th Interdisciplinary Meeting in Třešť

Her poster “Overcoming Colorectal Cancer Persistence: A Multi-Target Strategy Against Drug-Tolerant Cells” was selected as the best by participants. In addition, Matěj was among the five nominees for the best presentation. Congratulations!

22 Apr

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2-COL3A1 axis

New paper from our group has just been published in Molecular Oncology.

27 Mar

MjUNI in our lab

This year, the MjUNI juniors transformed monocytes into macrophages and immediately sent them into a battle for the title of the greatest predator. The phagocytic showdown and the hunt for differentiation antigens were ultimately surpassed by determining the lecturers’ blood groups.

5 Dec 2025

MYB - CKB - N-cadherin pathway controls migration of osteosarcoma cells

New publication in Cancer Cell International has just been published.

2 Dec 2025

Book Launch: "The Song of the Cell" translated by prof. Šmarda

On November 29, at the Brno Book Festival, MUNI Press introduced the Czech edition of Siddhartha Mukherjee’s latest work The Song of the Cell: Medicine and the New Human. The translation was prepared by Prof. Jan Šmarda. Mukherjee’s book offers a captivating journey through the history of cell research, interwoven with stories of patients, doctors, and scientists, highlighting how modern medicine is transforming our understanding of life and health.

1 Dec 2025

We spent our favourite weekend of the year in Růžená – Teambuilding 2025

Our LCD team enjoyed a wonderful teambuilding weekend in Růžena. We shared great meals, had lots of fun together, and explored the beautiful surrounding nature on a scenic trip.

28 Nov 2025

New Open-Source Tool for 3D Migration Analysis in Organoids and Spheroids

Our team has developed a publicly available software tool for quantitative analysis of cell migration in 3D models such as organoids and spheroids. Learn more in our recent publication in ACS Measurement Science Au. The ImageJ macro is available at: gitlab.fi.muni.cz

1 Sep 2025

Barbora Lujka joined our team as a new PhD student

A warm welcome to our lab. We wish Barbora inspiration and joy in her scientific journey!

1 Sep 2025

Co-author research articles published in 2025

Siatkowska et al. Tropomyosin isoforms encoded by TPM2 control the actin-bundling activity of fascin-1. Biol Res 2025. doi: 10.1186/s40659-025-00640-3

Jansova et al. Absence of CDK12 in oocyte leads to female infertility. Cell Death Dis 2025. doi: 10.1038/s41419-025-07536-w

14 May 2025

Visit and MUNI Life Science Seminar Lecture by prof. Lubor Borsig

In April, we were visited by our long-time collaborator, Prof. Lubor Borsig from the University of Zurich. During the visit, we discussed our ongoing projects, and at the end, Prof. Borsig gave a lecture on the role of the endothelium in the formation of metastases at the MUNI Life Science Seminar Series.

4 Apr 2025

Małgorzatas' erasmus internship visit

In March, we had a very pleasant visit from Polish Łódź. Dr. Małgorzata Gałdyszyńska was with us as an intern for a week, getting inspiration and sharing her experiences. It was a really nice and interesting enrichment for our working days.