Success of our student in the BYSCC competition

28 Jul

CRISPR-Cas10-Assisted Structural Modification of Staphylococcal Kayvirus for Imaging and Biosensing Applications

Šimečková et al. ACS Synthetic Biology 2025
Congratulations to Hanka on her publication of a structurally modified bacteriophage with a number of advanced applications.

24 Mar

We participated in the Electron Microscopy Days

11 Mar

Evidence of in vitro mecB-mediated β-lactam antibiotic resistance transfer to Staphylococcus aureus from Macrococcus psychrotolerans sp. nov., a psychrophilic bacterium from food-producing animals and human clinical specimens

Mašlaňová et al., Appl Environ Microbiol 2025
The study offers insights into the phenotypic and genomic features of new species Macrococcus psychrotolerans sp. nov. including first complete sequence of a linear 150-kb plasmid. Confirmed in vitro conjugative transfer of plasmid-borne mecB gene to S. aureus poses a significant risk of spread of broad β-lactam resistance including 5th generation cephalosporins.

30 Jan

Piezoelectric biosensor with dissipation monitoring enables the analysis of bacterial lytic agent activity

Obořilová R. et al., Scientific Reports 2025
We have published a novel approach to monitor the dynamics of lysis of pathogenic bacteria in real time using piezoelectric sensors. The results confirmed the effective synergy between bacteriophages and antibiotics in the action against Staphylococcus aureus, indicating that this is a promising strategy for the treatment of drug-resistant bacterial infections.