News

19 Jan

The pharmaceutical quality of freeze-dried tablets containing therapeutic bacteriophages against Pseudomonas aeruginosa and Staphylococcus aureus

Komárková et al., International Journal of Pharmaceutics 2025
Developing a quality dosage form containing bacteriophages is crucial for the practical application of phage therapy. We have published an article dealing with the processing of bacteriophages for treating P. aeruginosa and S. aureus infections into lyophilized tablets. The publication evaluated the quality of the resulting tablets according to pharmaceutical standards and the long-term stability of bacteriophages in this form. The publication was prepared together with colleagues from CEITEC VUT, FaF MUNI and MB Pharma s.r.o.

10 Jan

Permafrost as a source of mineral weathering bacteria: Implications of active layer thickening on James Ross Island, Antarctica

Micenková et al., CATENA 2025
Microbiological research in Antarctica provides a unique perspective on biodiversity and the influence of geochemistry on soil microbial composition. Samples from a 350 cm deep core were analyzed in the area of ​​the J. G. Mendel Czech Antarctic Station on James Ross Island. Geological transitions, such as the interface between the active layer and permafrost or the change between Holocene marine sediments and Cretaceous rocks, had a key influence on microbial composition. Due to warming, the interaction between microbial communities in the active layer and permafrost is expected to deepen in the future.

8 Oct 2024

Zúčastnili jsme se Noci vědců

8 Mar 2024

Effect of soil depth on the structure of bacterial composition in the active layer at five geologically distinct sites on James Ross and Vega Islands in Antarctica

Micenková et al., Polar Biology 2024
We have published what microbes we find in the surface layer above permafrost, known as the active layer, which thaws seasonally and is considered an important component of terrestrial ecosystems, where these microbes represent significant source of new bacterial species with potential, e.g., as a promising source of new antimicrobial compounds.

30 Nov 2023

Obdrželi jsme nový projekt TA ČR

Jorvik: a membrane-containing phage that will likely found a new family within Vinavirales

Congratulation to Pavol on to paper about new membrane-containing phage 

15 Jun 2023

Success of our student in the BYSCC competition

Congratulations! Our student Tomáš Chlubna was awarded 2nd shared place in the 42nd Beijing Youth Science Creation Competition (BYSCC) held online in Beijing, China! Tomáš presented his work “Phage therapy of ESKAPE group pathogens”.

Staphylococcus aureus Prophage-Encoded Protein Causes Abortive Infection and Provides Population Immunity against Kayviruses

Kuntová L. & Mašlaňová I. et al., mBio 2023
The first described system of abortive infection in staphylococci